{"id":1531,"date":"2026-04-05T14:09:40","date_gmt":"2026-04-05T14:09:40","guid":{"rendered":"https:\/\/www.presafe.co.uk\/?page_id=1531"},"modified":"2026-04-05T14:09:40","modified_gmt":"2026-04-05T14:09:40","slug":"heart-failure-what-next","status":"publish","type":"page","link":"https:\/\/www.presafe.co.uk\/","title":{"rendered":"HEART FAILURE  what next"},"content":{"rendered":"\n<p><strong>Recommended by the NHS for my Heart Failure<\/strong><\/p>\n\n\n\n<p><strong>Ramipril 3.73mg<\/strong> ACE inhibitor Relaxing blood vessels,<\/p>\n\n\n\n<p>Combining Ramipril &amp; Dapagliflozin requires caution due to an increased risk of hypotension (low blood pressure) and dehydration<\/p>\n\n\n\n<p><strong>Bisoprolol 2.5mg<\/strong> a beta-blocker, works by blocking the effects of hormones like adrenaline to slow the heart rate and lower blood pressure.<\/p>\n\n\n\n<p><strong>Dapagliflozin 10mg <\/strong>a SGLT2 inhibitor. Treats type 2 diabetes by forcing the kidneys to remove excess glucose through urine.<\/p>\n\n\n\n<p><strong>Furosemide 40mg<\/strong> Loop Diuretic. Treats fluid overload (oedema) and high blood pressure by inhibiting salt and water reabsorption in the kidneys.<\/p>\n\n\n\n<p>A<strong>pixaban 10mg<\/strong> oral anticoagulant. Blood thinner.<\/p>\n\n\n\n<p><strong>Atorvastatin 20mg<\/strong> PCSK9 inhibitor. First-line oral statin that reduces cholesterol production.<\/p>\n\n\n\n<p><strong>Omeprazole 20mg<\/strong> Pump Inhibitor acid reduction.<\/p>\n\n\n\n<p><strong>Spironolactone<\/strong> <strong>25mg<\/strong> heart failure, high blood pressure, PCOS potassium-sparing diuretic.&nbsp;<\/p>\n\n\n\n<p><strong>So what do they do in Japan, China &amp; India.<\/strong><\/p>\n\n\n\n<p><strong>Japan Collaborative Cohort Study (JACC<\/strong>), suggests a strong, evidence-based approach to using <strong>Coenzyme Q10 (CoQ10), astaxanthin, and Vitamin B12<\/strong> (along with<strong> B6\/folate<\/strong>) to support cardiovascular function. In Japan, CoQ10 is considered a legitimate treatment for heart failure, while recent pilot studies have highlighted <strong>astaxanthin<\/strong>\u2019s role in reducing cardiac oxidative stress.<\/p>\n\n\n\n<p><strong>Coenzyme Q10 (CoQ10) in Japan<\/strong><\/p>\n\n\n\n<p><strong>CoQ10<\/strong> was approved in Japan in 1974 for the treatment of congestive heart failure<\/p>\n\n\n\n<p><strong>Astaxanthin<\/strong> supplementation (12 mg\/day) suppressed oxidative stress (lowered dROM levels) and improved heart function (ejection fraction) in patients with heart failure.<\/p>\n\n\n\n<p><strong>B vitamins<\/strong> (specifically <strong>folic acid and B12<\/strong>) were inversely associated with mortality from cardiovascular diseases.<\/p>\n\n\n\n<p><strong>B12\/folate<\/strong> intake was linked to a lower risk of stroke and heart failure.<\/p>\n\n\n\n<p><strong>B12, alongside B6 and folate<\/strong>, break down homocysteine, which damages inner lining of arteries.<\/p>\n\n\n\n<p><strong>Vitamin D3 and K2<\/strong> is considered a potent &#8220;dynamic duo&#8221; for cardiovascular health.<\/p>\n\n\n\n<p><strong>Magnesium<\/strong> linked to a lower risk of mortality from ischemic stroke and coronary heart disease.<\/p>\n\n\n\n<p>Plays a key role in regulating blood pressure, crucial for preventing cardiovascular issues.<\/p>\n\n\n\n<p><strong>Omega-3s EPA and DHA<\/strong> intake reduce the risk of coronary heart disease, especially for those who are considered to be in a \u201chigher risk population\u201d such as those with higher blood triglyceride<\/p>\n\n\n\n<p><strong>Selenium <\/strong>is an essential mineral with antioxidant properties that help prevent atherosclerosis and maintain heart health. Improves blood rheological properties (fluidity). Heart Failure Risks: <strong>selenium<\/strong> deficiency is not uncommon in heart failure patients its deficiency is linked to higher 1-year mortality and readmission rates.<\/p>\n\n\n\n<p><strong>Zinc and vitamin C<\/strong> support your immune system, reducing the risk of several diseases like heart disease and stroke<\/p>\n\n\n\n<p><strong>Quercetin<\/strong> is a naturally occurring plant pigment and one of the most abundant dietary <strong>flavonoids<\/strong>, known for its potent antioxidant and anti-inflammatory properties.<\/p>\n\n\n\n<p><strong>Vit C 500mg + Zinc15mg<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Vit D3 10000IU + K2 200mcg<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>CQ10 200mg<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Magnesium Elemental 150mg<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Milti B Vits 75mg each<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Vit B12 250ug<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Folic Acid 400ug<\/strong> <strong>Astaxanthin 18mg<\/strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Selenium 200mcg<\/strong>&nbsp;&nbsp;&nbsp; <strong>Omega 369 1000mg<\/strong>&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Quercetin 500mg<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recommended by the NHS for my Heart Failure Ramipril 3.73mg ACE inhibitor Relaxing blood vessels, Combining Ramipril &amp; Dapagliflozin requires caution due to an increased risk of hypotension (low blood pressure) and dehydration Bisoprolol 2.5mg a beta-blocker, works by blocking the effects of hormones like adrenaline to slow the heart rate and lower blood pressure. &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.presafe.co.uk\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;HEART FAILURE  what next&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false},"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P8RUXD-oH","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=\/wp\/v2\/pages\/1531"}],"collection":[{"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1531"}],"version-history":[{"count":1,"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=\/wp\/v2\/pages\/1531\/revisions"}],"predecessor-version":[{"id":1532,"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=\/wp\/v2\/pages\/1531\/revisions\/1532"}],"wp:attachment":[{"href":"https:\/\/www.presafe.co.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}